Testa Challenge 2022
Testa Challenge 2022
The Testa Challenge 2022 bioprocess workflow – specifications
A start to finish bioprocess producing and purifying a monoclonal antibody (mAb).
Process outline:
- Monoclonal antibody (mAb) production in CHO cells through a fed-batch process in a single-use stirred-tank 50L bioreactor
- Clarification of CHO culture using depth filtration
- Isolation and purification of the produced mAb with an affinity chromatography step followed by an additional polishing step to reduce impurities
- The quality of the produced, purified monoclonal antibody (mAb) will be assessed using various analytical techniques
Scitara
Scitara provides a digital platform that enables seamless, automated data exchange across laboratory instruments and software, improving productivity and data integrity.
Their solution eliminates manual steps in lab workflows, ensuring compliance and accelerating scientific discovery.
By streamlining data flow in regulated environments like pharma and biotech, Scitara supports faster innovation and enhances collaboration between research, development, and manufacturing teams.
Nyctea
Nyctea delivers a new solution for non-invasive processing of biopharmaceuticals for improved productivity resulting in affordable medicine for patients.
The company is based on an invention of a surface that purifies biomolecules by electronic signals that replace the use of problematic chemicals in the production process, giving faster production and higher yield.
Their product enables manufacture of more kinds of biopharmaceuticals and accelerates the development of new treatments against diseases.
AnalysisMode
AnalysisMode has developed an AI-powered bioprocessing simulator to better design, model, and execute bioprocesses.
Their bioprocess simulator assists scientists to make data-based and more informed decisions therefore saving time, costs, and energy.
AnalysisMode's mission is to model bioprocesses across different products and therapies to make treatments accessible to everyone. They believe that by using their solution, stakeholders can cut down costs drastically and gain insights not possible with already existing technologies.
Timegate
Timegate Instruments offers innovative time-gated Raman spectroscopy solutions for real-time material analysis.
Their patented technology filters out background fluorescence, enabling precise chemical identification even in complex environments.
This allows non-invasive, real-time monitoring in pharmaceutical and industrial processes, improving accuracy, speeding up development, and reducing the need for offline testing.
Argus Eye
Argus Eye offers a compact optical sensor system that enables real-time, in-line particle monitoring in bioprocesses.
Their patented light-scattering technology detects changes in particle size and concentration, providing early warnings of process deviations.
This supports better process control, increased efficiency, and improved product quality in the production of biologics and cell-based therapies.